| Host: |
Goat |
| Applications: |
Pep-ELISA/WB |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Goat polyclonal antibody anti-AOC3/VAP1 (Internal) is suitable for use in ELISA and Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Purification: |
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Concentration: |
0.5 mg/mL |
| Dilution Range: |
Peptide ELISA: antibody detection limit dilution 1:128000.WB: Approx 90kDa band observed in lysates of cell line A549 (calculated MW of 84.6kDa according to NP_003725.1). Recommended concentration: 0.1-0.3µg/ml.An additional band of unknown iden |
| Storage Instruction: |
Store at-20°C on receipt and minimise freeze-thaw cycles. |
| Gene Symbol: |
AOC3 |
| Gene ID: |
8639 |
| Uniprot ID: |
AOC3_HUMAN |
| Immunogen Region: |
Internal |
| Accession Number: |
NP_003725.1 |
| Immunogen Sequence: |
ESQAPKTIRDAFC |
| Post Translational Modifications | Topaquinone (TPQ) is generated by copper-dependent autoxidation of a specific tyrosyl residue. N- and O-glycosylated. |
| Function | Catalyzes the oxidative deamination of primary amines to the corresponding aldehydes with the concomitant production of hydrogen peroxide and ammonia. Has a preference for the primary monoamines methylamine and benzylamine. Could also act on 2-phenylethylamine but much less efficiently. At endothelial cells surface can also function as a cell adhesion protein that participates in lymphocyte extravasation and recirculation by mediating the binding of lymphocytes to peripheral lymph node vascular endothelial cells in an L-selectin-independent fashion. Isoform 2: Has no semicarbazide-sensitive amine oxidase (SSAO) activity. |
| Protein Name | Amine Oxidase Copper-Containing 3Amine Oxidase Copper-Containing 3Copper Amine OxidaseHpaoSemicarbazide-Sensitive Amine OxidaseSsaoVascular Adhesion Protein 1Vap-1 |
| Database Links | Reactome: R-HSA-211945 |
| Cellular Localisation | Cell MembraneSingle-Pass Type Ii Membrane Protein |
| Alternative Antibody Names | Anti-Amine Oxidase Copper-Containing 3 antibodyAnti-Amine Oxidase Copper-Containing 3 antibodyAnti-Copper Amine Oxidase antibodyAnti-Hpao antibodyAnti-Semicarbazide-Sensitive Amine Oxidase antibodyAnti-Ssao antibodyAnti-Vascular Adhesion Protein 1 antibodyAnti-Vap-1 antibodyAnti-AOC3 antibodyAnti-VAP1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
