| Tissue Specificity | Detected in epithelial cells in colon and jejunum (at protein level). Detected in epithelial cells in jejunum. |
| Function | Isoform A: Binds to membranes enriched in phosphatidylserine or phosphatidylglycerol in a calcium-dependent manner. Half-maximal membrane binding requires about 60 uM calcium. Does not bind to membranes that lack phospholipids with an acidic headgroup. Isoform B: Binds to membranes enriched in phosphatidylserine or phosphatidylglycerol in a calcium-dependent manner, but requires higher calcium levels for membrane binding than isoform A. Half-maximal membrane binding requires about 320 uM calcium. |
| Protein Name | Annexin A13Annexin XiiiAnnexin-13Intestine-Specific AnnexinIsa |
| Database Links | |
| Cellular Localisation | Apical Cell MembraneCell MembraneLipid-AnchorCytoplasmic VesicleMyristoylation Anchors The Protein To The MembraneBut The Protein Also Displays Calcium-DependentReversible Binding To Lipid MembranesAssociated With The Plasma Membrane Of UndifferentiatedProliferating Crypt Epithelial Cells As Well As Differentiated Villus Enterocytes |
| Alternative Antibody Names | Anti-Annexin A13 antibodyAnti-Annexin Xiii antibodyAnti-Annexin-13 antibodyAnti-Intestine-Specific Annexin antibodyAnti-Isa antibodyAnti-ANXA13 antibodyAnti-ANX13 antibody |
Information sourced from Uniprot.org
