Host: | Rabbit |
Applications: | WB/ELISA |
Reactivity: | Mouse |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Clonality: | Monoclonal |
Clone ID: | S7MR |
Conjugation: | Unconjugated |
Isotype: | IgG |
Formulation: | PBS with 0.02% Sodium Azide, 0.05% BSA, 50% Glycerol, pH 7.3. |
Purification: | Affinity purification |
Concentration: | Lot specific |
Dilution Range: | WB:1:500-1:1000 ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: | NPR2 |
Gene ID: | 4882 |
Uniprot ID: | ANPRB_HUMAN |
Immunogen Region: | 800-900 |
Specificity: | A synthetic peptide corresponding to a sequence within amino acids 800-900 of human ANPRB/NRP2 (P20594). |
Immunogen Sequence: | NLLLRMEQYANNLEKLVEER TQAYLEEKRKAEALLYQILP HSVAEQLKRGETVQAEAFDS VTIYFSDIVGFTALSAESTP MQVVTLLNDLYTCFDAIIDN F |
Post Translational Modifications | Phosphorylated. Phosphorylation of the protein kinase-like domain is required for full activation by CNP. Glycosylated. |
Function | Receptor for the C-type natriuretic peptide NPPC/CNP hormone. Has guanylate cyclase activity upon binding of its ligand. May play a role in the regulation of skeletal growth. |
Protein Name | Atrial Natriuretic Peptide Receptor 2 Atrial Natriuretic Peptide Receptor Type B Anp-B Anpr-B Npr-B Guanylate Cyclase B Gc-B |
Database Links | Reactome: R-HSA-5578768 |
Cellular Localisation | Cell Membrane Single-Pass Type I Membrane Protein |
Alternative Antibody Names | Anti-Atrial Natriuretic Peptide Receptor 2 antibody Anti-Atrial Natriuretic Peptide Receptor Type B antibody Anti-Anp-B antibody Anti-Anpr-B antibody Anti-Npr-B antibody Anti-Guanylate Cyclase B antibody Anti-Gc-B antibody Anti-NPR2 antibody Anti-ANPRB antibody |
Information sourced from Uniprot.org