Anti-ANPRB/NRP2 antibody (800-900) [S7MR] (STJ11102987)

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STJ11102987
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Host: Rabbit
Applications: WB/ELISA
Reactivity: Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality : Monoclonal
Clone ID : S7MR
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.02% Sodium Azide, 0.05% BSA, 50% Glycerol, pH 7.3.
Purification: Affinity purification
Concentration: Lot specific
Dilution Range: WB:1:500-1:1000
ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: NPR2
Gene ID: 4882
Uniprot ID: ANPRB_HUMAN
Immunogen Region: 800-900
Specificity: A synthetic peptide corresponding to a sequence within amino acids 800-900 of human ANPRB/NRP2 (P20594).
Immunogen Sequence: NLLLRMEQYANNLEKLVEER TQAYLEEKRKAEALLYQILP HSVAEQLKRGETVQAEAFDS VTIYFSDIVGFTALSAESTP MQVVTLLNDLYTCFDAIIDN F
Post Translational Modifications Phosphorylated. Phosphorylation of the protein kinase-like domain is required for full activation by CNP. Glycosylated.
Function Receptor for the C-type natriuretic peptide NPPC/CNP hormone. Has guanylate cyclase activity upon binding of its ligand. May play a role in the regulation of skeletal growth.
Protein Name Atrial Natriuretic Peptide Receptor 2
Atrial Natriuretic Peptide Receptor Type B
Anp-B
Anpr-B
Npr-B
Guanylate Cyclase B
Gc-B
Database Links Reactome: R-HSA-5578768
Cellular Localisation Cell Membrane
Single-Pass Type I Membrane Protein
Alternative Antibody Names Anti-Atrial Natriuretic Peptide Receptor 2 antibody
Anti-Atrial Natriuretic Peptide Receptor Type B antibody
Anti-Anp-B antibody
Anti-Anpr-B antibody
Anti-Npr-B antibody
Anti-Guanylate Cyclase B antibody
Anti-Gc-B antibody
Anti-NPR2 antibody
Anti-ANPRB antibody

Information sourced from Uniprot.org