Anti-ANPRB/NRP2 antibody (800-900) [S7MR] (STJ11102987)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit monoclonal ANPRB/NRP2 (800-900) antibody for use in WB and ELISA in mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | S7MR |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:1000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 0.05% BSA, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | NPR2 |
| Gene ID | 4882 |
| Uniprot ID | ANPRB_HUMAN |
| Immunogen Region | 800-900 |
| Immunogen Sequence | NLLLRMEQYANNLEKLVEER TQAYLEEKRKAEALLYQILP HSVAEQLKRGETVQAEAFDS VTIYFSDIVGFTALSAESTP MQVVTLLNDLYTCFDAIIDN F |
| Specificity | A synthetic peptide corresponding to a sequence within amino acids 800-900 of human ANPRB/NRP2 (P20594). |
Additional Info
| Post Translational Modifications | Phosphorylated. Phosphorylation of the protein kinase-like domain is required for full activation by CNP. Glycosylated. |
| Function | Receptor for the C-type natriuretic peptide NPPC/CNP hormone. Has guanylate cyclase activity upon binding of its ligand. May play a role in the regulation of skeletal growth. |
| Protein Name | Atrial Natriuretic Peptide Receptor 2Atrial Natriuretic Peptide Receptor Type BAnp-BAnpr-BNpr-BGuanylate Cyclase BGc-B |
| Database Links | Reactome: R-HSA-5578768 |
| Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane Protein |
| Alternative Antibody Names | Anti-Atrial Natriuretic Peptide Receptor 2 antibodyAnti-Atrial Natriuretic Peptide Receptor Type B antibodyAnti-Anp-B antibodyAnti-Anpr-B antibodyAnti-Npr-B antibodyAnti-Guanylate Cyclase B antibodyAnti-Gc-B antibodyAnti-NPR2 antibodyAnti-ANPRB antibody |
Information sourced from Uniprot.org