| Applications: | WB/ELISA |
| Host: | Rabbit |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | Lot specific |
| Purification: | Affinity purification |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation: | PBS with 0.05% Proclin300, 50% Glycerol, pH 7.3. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | ANGPTL8 |
| Gene ID: | 55908 |
| Uniprot ID: | ANGL8_HUMAN |
| Immunogen Region: | 22-198 |
| Immunogen Sequence: | APMGGPELAQHEELTLLFHG TLQLGQALNGVYRTTEGRLT KARNSLGLYGRTIELLGQEV SRGRDAAQELRASLLETQME EDILQLQAEATAEVLGEVAQ AQKVLRDSVQRLEVQLRSAW LGPAYREFEVLKAHADKQSH ILWALTGHVQRQRREMVAQQ HRLRQIQERLHTAALPA |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 22-198 of human ANGPTL8 (NP_061157.3). |
| Tissue Specificity | Predominantly expressed in liver. Also expressed in adipose tissues. |
| Post Translational Modifications | Proteolytically cleaved at the N-terminus. |
| Function | Hormone that acts as a blood lipid regulator by regulating serum triglyceride levels. May be involved in the metabolic transition between fasting and refeeding: required to direct fatty acids to adipose tissue for storage in the fed state. |
| Protein Name | Angiopoietin-Like Protein 8BetatrophinLipasinRefeeding-Induced Fat And Liver Protein |
| Database Links | Reactome: R-HSA-8963889 |
| Cellular Localisation | Secreted |
| Alternative Antibody Names | Anti-Angiopoietin-Like Protein 8 antibodyAnti-Betatrophin antibodyAnti-Lipasin antibodyAnti-Refeeding-Induced Fat And Liver Protein antibodyAnti-ANGPTL8 antibodyAnti-C19orf80 antibodyAnti-RIFL antibodyAnti-UNQ599 antibodyAnti-PRO1185 antibody |
Information sourced from Uniprot.org
