| Host: | Rabbit |
| Applications: | IHC/IF/ELISA |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-Angiomotin-like protein 1 (441-490 aa) is suitable for use in Immunohistochemistry, Immunofluorescence and ELISA research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | IHC 1:100-1:300ELISA 1:10000IF 1:50-200 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | AMOTL1 |
| Gene ID: | 154810 |
| Uniprot ID: | AMOL1_HUMAN |
| Immunogen Region: | 441-490 aa |
| Specificity: | Angiomotin-L1 Polyclonal Antibody detects endogenous levels of Angiomotin-L1 protein. |
| Immunogen: | The antiserum was produced against synthesized peptide derived from the human AMOTL1 at the amino acid range 441-490 |
| Function | Inhibits the Wnt/beta-catenin signaling pathway, probably by recruiting CTNNB1 to recycling endosomes and hence preventing its translocation to the nucleus. |
| Protein Name | Angiomotin-Like Protein 1 |
| Database Links | Reactome: R-HSA-2028269 |
| Cellular Localisation | Cell JunctionTight Junction |
| Alternative Antibody Names | Anti-Angiomotin-Like Protein 1 antibodyAnti-AMOTL1 antibody |
Information sourced from Uniprot.org