| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Rat/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-Amphoterin-induced protein 2 (270-350 aa) is suitable for use in Western Blot and ELISA research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-2000ELISA 1:5000-20000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | AMIGO2 |
| Gene ID: | 347902 |
| Uniprot ID: | AMGO2_HUMAN |
| Immunogen Region: | 270-350 aa |
| Specificity: | AMGO2 Polyclonal Antibody detects endogenous levels of protein. |
| Immunogen: | Synthesized peptide derived from the human protein at the amino acid range 270-350 |
| Function | Required for depolarization-dependent survival of cultured cerebellar granule neurons. May mediate homophilic as well as heterophilic cell-cell interaction with AMIGO1 or AMIGO3. May contribute to signal transduction through its intracellular domain. May be required for tumorigenesis of a subset of gastric adenocarcinomas. |
| Protein Name | Amphoterin-Induced Protein 2Amigo-2Alivin-1Differentially Expressed In Gastric AdenocarcinomasDega |
| Database Links | Reactome: R-HSA-9013149Reactome: R-HSA-9013423 |
| Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane ProteinNucleusAssociated With Nucleus As Well As Plasma MembraneRestricted To Somata Of Cerebellar As Well As Hippocampal Neurons |
| Alternative Antibody Names | Anti-Amphoterin-Induced Protein 2 antibodyAnti-Amigo-2 antibodyAnti-Alivin-1 antibodyAnti-Differentially Expressed In Gastric Adenocarcinomas antibodyAnti-Dega antibodyAnti-AMIGO2 antibodyAnti-ALI1 antibody |
Information sourced from Uniprot.org