| Host: | Rabbit, Mouse |
| Applications: | IHC-P |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit, Mouse monoclonal antibody anti-AMACR+P63+HMW CK is suitable for use in Immunohistochemistry research applications. |
| Clonality : | Monoclonal |
| Clone ID : | 13H4+ZM70+34 Beta E12 |
| Conjugation: | Unconjugated |
| Isotype: | IgG, IgG1 + IgG2a |
| Formulation: | Tris-HCI buffer containing stabilizing protein (BSA) and <0.1% ProClin |
| Purification: | Affinity purified |
| Dilution Range: | 1:50 |
| Storage Instruction: | Store at 2‐8°C for up to 24 months. Predilute: Ready to use, no reconstitution necessary. Concentrate: Use dilution range and appropriate lab‐standardized diluent. Stability after dilution: 7 days at 24°C, 3 months at 2‐8°C, 6months at ‐20°C. |
| Gene Symbol: | AMACR |
| Gene ID: | 23600 |
| Uniprot ID: | AMACR_HUMAN |
| Specificity: | Positive control: Prostate intraepithelial neoplasia (PIN) |
| Immunogen: | Human AMACR (P504S) , p63, and CKHMW (34 Beta E12) polypeptides |
| Function | Catalyzes the interconversion of (R)- and (S)-stereoisomers of alpha-methyl-branched-chain fatty acyl-CoA esters. Acts only on coenzyme A thioesters, not on free fatty acids, and accepts as substrates a wide range of alpha-methylacyl-CoAs, including pristanoyl-CoA, trihydroxycoprostanoyl-CoA (an intermediate in bile acid synthesis), and arylpropionic acids like the anti-inflammatory drug ibuprofen (2-(4-isobutylphenyl)propionic acid) but neither 3-methyl-branched nor linear-chain acyl-CoAs. |
| Protein Name | Alpha-Methylacyl-Coa Racemase2-Methylacyl-Coa Racemase |
| Database Links | Reactome: R-HSA-193368Reactome: R-HSA-193775Reactome: R-HSA-389887Reactome: R-HSA-9033241 |
| Cellular Localisation | PeroxisomeMitochondrion |
| Alternative Antibody Names | Anti-Alpha-Methylacyl-Coa Racemase antibodyAnti-2-Methylacyl-Coa Racemase antibodyAnti-AMACR antibody |
Information sourced from Uniprot.org
