| Short Description : | Rabbit polyclonal AGXT (183-392) antibody for use in WB, IHC-P and ELISA in human and mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | WB/IHC-P/ELISA |
| Host: | Rabbit |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | Lot specific |
| Purification: | Affinity purification |
| Dilution Range: | WB:1:500-1:2000IHC-P:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | AGXT |
| Gene ID: | 189 |
| Uniprot ID: | AGT1_HUMAN |
| Immunogen Region: | 183-392 |
| Immunogen Sequence: | DSVASLGGTPLYMDRQGIDI LYSGSQKALNAPPGTSLISF SDKAKKKMYSRKTKPFSFYL DIKWLANFWGCDDQPRMYHH TIPVISLYSLRESLALIAEQ GLENSWRQHREAAAYLHGRL QALGLQLFVKDPALRLPTVT TVAVPAGYDWRDIVSYVIDH FDIEIMGGLGPSTGKVLRIG LLGCNATRENVDRVTEALRA ALQHCPKKKL |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 183-392 of human AGXT (NP_000021.1). |
| Tissue Specificity | Liver. |
| Function | Peroxisomal aminotransferase that catalyzes the transamination of glyoxylate to glycine and contributes to the glyoxylate detoxification. Also catalyzes the transamination between L-serine and pyruvate and contributes to gluconeogenesis from the L-serine metabolism. |
| Protein Name | Alanine--Glyoxylate AminotransferaseAgtSerine--Pyruvate AminotransferaseSpt |
| Database Links | Reactome: R-HSA-389661Reactome: R-HSA-9033241 |
| Cellular Localisation | Peroxisome |
| Alternative Antibody Names | Anti-Alanine--Glyoxylate Aminotransferase antibodyAnti-Agt antibodyAnti-Serine--Pyruvate Aminotransferase antibodyAnti-Spt antibodyAnti-AGXT antibodyAnti-AGT1 antibodyAnti-SPAT antibody |
Information sourced from Uniprot.org
