| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-Type-1 angiotensin II receptor-associated protein is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: |
1 mg/mL |
| Dilution Range: |
WB 1:500-2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
AGTRAP |
| Gene ID: |
57085 |
| Uniprot ID: |
ATRAP_HUMAN |
| Specificity: |
This antibody detects endogenous levels of AGTRAP at Human, Mouse, Rat |
| Immunogen: |
Synthesized peptide derived from human AGTRAP |
| Function | Appears to be a negative regulator of type-1 angiotensin II receptor-mediated signaling by regulating receptor internalization as well as mechanism of receptor desensitization such as phosphorylation. Induces also a decrease in cell proliferation and angiotensin II-stimulated transcriptional activity. |
| Protein Name | Type-1 Angiotensin Ii Receptor-Associated ProteinAt1 Receptor-Associated Protein |
| Database Links | Reactome: R-HSA-6802952 |
| Cellular Localisation | Endoplasmic Reticulum MembraneMulti-Pass Membrane ProteinGolgi Apparatus MembraneCytoplasmic Vesicle MembranePresent In Perinuclear Vesicular MembranesEndoplasmic ReticulumGolgi And Endocytic Vesicles |
| Alternative Antibody Names | Anti-Type-1 Angiotensin Ii Receptor-Associated Protein antibodyAnti-At1 Receptor-Associated Protein antibodyAnti-AGTRAP antibodyAnti-ATRAP antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
