| Tissue Specificity | Widely expressed with highest levels in testis, pancreas and kidney, followed by spleen, lung, adipose tissue and liver. |
| Function | Converts 1-acyl-sn-glycerol-3-phosphate (lysophosphatidic acid or LPA) into 1,2-diacyl-sn-glycerol-3-phosphate (phosphatidic acid or PA) by incorporating an acyl moiety at the sn-2 position of the glycerol backbone. Acts on LPA containing saturated or unsaturated fatty acids C16:0-C20:4 at the sn-1 position using C18:1, C20:4 or C18:2-CoA as the acyl donor. Also acts on lysophosphatidylcholine, lysophosphatidylinositol and lysophosphatidylserine using C18:1 or C20:4-CoA. Has a preference for arachidonoyl-CoA as a donor. Also has a modest lysophosphatidylinositol acyltransferase (LPIAT) activity, converts lysophosphatidylinositol (LPI) into phosphatidylinositol. |
| Protein Name | 1-Acyl-Sn-Glycerol-3-Phosphate Acyltransferase Gamma1-Acylglycerol-3-Phosphate O-Acyltransferase 31-Agp Acyltransferase 31-Agpat 3Lysophosphatidic Acid Acyltransferase GammaLpaat-Gamma |
| Database Links | Reactome: R-HSA-1483166Reactome: R-HSA-6811436 |
| Cellular Localisation | Endoplasmic Reticulum MembraneMulti-Pass Membrane ProteinNucleus Envelope |
| Alternative Antibody Names | Anti-1-Acyl-Sn-Glycerol-3-Phosphate Acyltransferase Gamma antibodyAnti-1-Acylglycerol-3-Phosphate O-Acyltransferase 3 antibodyAnti-1-Agp Acyltransferase 3 antibodyAnti-1-Agpat 3 antibodyAnti-Lysophosphatidic Acid Acyltransferase Gamma antibodyAnti-Lpaat-Gamma antibodyAnti-AGPAT3 antibodyAnti-LPAAT3 antibodyAnti-UNQ759 antibodyAnti-PRO1490 antibody |
Information sourced from Uniprot.org
