Anti-AGFG1 antibody (1-280) (STJ115461)

Name: Anti-AGFG1 antibody (1-280) (STJ115461)
SKU: STJ115461
Availability: InStock

⇓ Datasheet ⇓ SDS

SPECIFICATIONS

ClonalityPolyclonal

HostRabbit

ConjugationUnconjugated

IsotypeIgG

STJ115461

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Short Description	Rabbit polyclonal AGFG1 (1-280) antibody for use in WB and ELISA in human and mouse samples. Datasheet included with dilution recommendations, and related reagents.
Applications	WB/ELISA
Host	Rabbit
Reactivity	Human/Mouse
Note	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Clonality	Polyclonal
Isotype	IgG
Conjugation	Unconjugated
Concentration	Lot specific
Purification	Affinity purification
Dilution Range	WB:1:500-1:2000 ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Formulation	PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3.
Storage Instruction	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol	AGFG1
Gene ID	3267
Uniprot ID	AGFG1_HUMAN
Immunogen Region	1-280
Immunogen Sequence	MAASAKRKQEEKHLKMLRDM TGLPHNRKCFDCDQRGPTYV NMTVGSFVCTSCSGSLRGLN PPHRVKSISMTTFTQQEIEF LQKHGNEVCKQIWLGLFDDR SSAIPDFRDPQKVKEFLQEK YEKKRWYVPPEQAKVVASVH ASISGSSASSTSSTPEVKPL KSLLGDSAPTLHLNKGTPSQ SPVVGRSQGQQQEKKQFDLL SDLGSDIFAAPAPQSTATAN FANFAHFNSHAAQNSANAD
Specificity	Recombinant fusion protein containing a sequence corresponding to amino acids 1-280 of human AGFG1 (NP_004495.2).

Tissue Specificity	Ubiquitously expressed.
Post Translational Modifications	O-glycosylated.
Function	Required for vesicle docking or fusion during acrosome biogenesis. May play a role in RNA trafficking or localization. In case of infection by HIV-1, acts as a cofactor for viral Rev and promotes movement of Rev-responsive element-containing RNAs from the nuclear periphery to the cytoplasm. This step is essential for HIV-1 replication.
Protein Name	Arf-Gap Domain And Fg Repeat-Containing Protein 1 Hiv-1 Rev-Binding Protein Nucleoporin-Like Protein Rip Rev-Interacting Protein Rev/Rex Activation Domain-Binding Protein
Database Links	Reactome: R-HSA-8856825 Reactome: R-HSA-8856828
Cellular Localisation	Nucleus Cytoplasmic Vesicle
Alternative Antibody Names	Anti-Arf-Gap Domain And Fg Repeat-Containing Protein 1 antibody Anti-Hiv-1 Rev-Binding Protein antibody Anti-Nucleoporin-Like Protein Rip antibody Anti-Rev-Interacting Protein antibody Anti-Rev/Rex Activation Domain-Binding Protein antibody Anti-AGFG1 antibody Anti-HRB antibody Anti-RAB antibody Anti-RIP antibody

Information sourced from Uniprot.org