Anti-AGBL5 antibody (499-549 aa) (STJ194382)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from the human CBPC5 at the amino acid range 499-549
General Information
| Short Description | Rabbit polyclonal anti-Cytosolic carboxypeptidase-like protein 5 (499-549 aa) for use in WB in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | AGBL5 |
| Gene ID | 60509 |
| Uniprot ID | CBPC5_HUMAN |
| Immunogen | Synthesized peptide derived from the human CBPC5 at the amino acid range 499-549 |
| Immunogen Region | 499-549 aa |
| Specificity | This antibody detects endogenous levels of CBPC5 at Human/Mouse/Rat |
Additional Info
| Function | Metallocarboxypeptidase that mediates deglutamylation of tubulin and non-tubulin target proteins. Catalyzes the removal of polyglutamate side chains present on the gamma-carboxyl group of glutamate residues within the C-terminal tail of alpha- and beta-tubulin. Cleaves alpha- and gamma-linked polyglutamate tubulin side-chain, as well as the branching point glutamate. Also catalyzes the removal of alpha-linked glutamate residues from the carboxy-terminus of alpha-tubulin. Mediates deglutamylation of nucleotidyltransferase CGAS, leading to CGAS antiviral defense response activation. |
| Protein Name | Cytosolic Carboxypeptidase-Like Protein 5Atp/Gtp-Binding Protein-Like 5Protein Deglutamylase Ccp5 |
| Database Links | Reactome: R-HSA-8955332 |
| Cellular Localisation | CytoplasmCytosolNucleusCytoskeletonSpindleMidbodyMainly CytoplasmicSlight Accumulation In The Nucleus Is ObservedColocalizes With Alpha-Tubulin In The Mitotic Spindle And With Midbody Microtubules In The Intercellular Bridges Formed During Cytokinesis |
| Alternative Antibody Names | Anti-Cytosolic Carboxypeptidase-Like Protein 5 antibodyAnti-Atp/Gtp-Binding Protein-Like 5 antibodyAnti-Protein Deglutamylase Ccp5 antibodyAnti-AGBL5 antibodyAnti-CCP5 antibody |
Information sourced from Uniprot.org