Anti-AFP antibody [C2] (STJ16100499)

SPECIFICATIONS
ClonalityMonoclonal
HostMouse
ConjugationUnconjugated
IsotypeIgG1k
ImmunogenA BALB/c mouse was immunized with alpha fetoprotein isolated from serum of hepatoma patients. Fusion partner: SP2/0.
STJ16100499
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General Information

Short DescriptionMouse monoclonal anti-Alpha fetoprotein for use in ELISA, FC, IF and IHC in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents.
ApplicationsELISA/FC/IF/IHC
HostMouse
ReactivityHuman/Mouse
NoteSTRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Product Properties

ClonalityMonoclonal
Clone IDC2
IsotypeIgG1k
ConjugationUnconjugated
ConcentrationCan be provided as 100 ยตg/mL, 500 ยตg/mL or 1mg/mL.
PurificationAffinity purified from tissue culture.
Dilution RangeELISA (solid phase: 0, 1-100 ยตg/ml; tracer: 0, 001-100 ยตg/ml for 30 min at RT). Flow cytometry (0, 5-1, 0 ยตg/million cells in 0, 1 ml). Immunofluorescence (0, 5-1 ยตg/ml). Immunohistology (formalin-fixed: 1-2 ยตg/ml for 30 min at RT: staining of formal
FormulationPBS with 0.02% Sodium Azide.
Storage InstructionStore for up to 1 year at 2-8ยฐC upon receipt.

Target Information

Gene SymbolAFP
Gene ID174
Uniprot IDFETA_HUMAN
ImmunogenA BALB/c mouse was immunized with alpha fetoprotein isolated from serum of hepatoma patients. Fusion partner: SP2/0.

Additional Info

Tissue Specificity Plasma. Synthesized by the fetal liver and yolk sac.
Post Translational Modifications Independent studies suggest heterogeneity of the N-terminal sequence of the mature protein and of the cleavage site of the signal sequence. Sulfated.
Function Binds copper, nickel, and fatty acids as well as, and bilirubin less well than, serum albumin. Only a small percentage (less than 2%) of the human AFP shows estrogen-binding properties.
Protein Name Alpha-Fetoprotein
Alpha-1-Fetoprotein
Alpha-Fetoglobulin
Database Links Reactome: R-HSA-381426
Reactome: R-HSA-8957275
Cellular Localisation Secreted
Alternative Antibody Names Anti-Alpha-Fetoprotein antibody
Anti-Alpha-1-Fetoprotein antibody
Anti-Alpha-Fetoglobulin antibody
Anti-AFP antibody
Anti-HPAFP antibody

Information sourced from Uniprot.org

Citations

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