Anti-AFP antibody [C2] (STJ16100499)
SPECIFICATIONS
ClonalityMonoclonal
HostMouse
ConjugationUnconjugated
IsotypeIgG1k
ImmunogenA BALB/c mouse was immunized with alpha fetoprotein isolated from serum of hepatoma patients. Fusion partner: SP2/0.
General Information
| Short Description | Mouse monoclonal anti-Alpha fetoprotein for use in ELISA, FC, IF and IHC in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | ELISA/FC/IF/IHC |
| Host | Mouse |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | C2 |
| Isotype | IgG1k |
| Conjugation | Unconjugated |
| Concentration | Can be provided as 100 ยตg/mL, 500 ยตg/mL or 1mg/mL. |
| Purification | Affinity purified from tissue culture. |
| Dilution Range | ELISA (solid phase: 0, 1-100 ยตg/ml; tracer: 0, 001-100 ยตg/ml for 30 min at RT). Flow cytometry (0, 5-1, 0 ยตg/million cells in 0, 1 ml). Immunofluorescence (0, 5-1 ยตg/ml). Immunohistology (formalin-fixed: 1-2 ยตg/ml for 30 min at RT: staining of formal |
| Formulation | PBS with 0.02% Sodium Azide. |
| Storage Instruction | Store for up to 1 year at 2-8ยฐC upon receipt. |
Target Information
| Gene Symbol | AFP |
| Gene ID | 174 |
| Uniprot ID | FETA_HUMAN |
| Immunogen | A BALB/c mouse was immunized with alpha fetoprotein isolated from serum of hepatoma patients. Fusion partner: SP2/0. |
Additional Info
| Tissue Specificity | Plasma. Synthesized by the fetal liver and yolk sac. |
| Post Translational Modifications | Independent studies suggest heterogeneity of the N-terminal sequence of the mature protein and of the cleavage site of the signal sequence. Sulfated. |
| Function | Binds copper, nickel, and fatty acids as well as, and bilirubin less well than, serum albumin. Only a small percentage (less than 2%) of the human AFP shows estrogen-binding properties. |
| Protein Name | Alpha-FetoproteinAlpha-1-FetoproteinAlpha-Fetoglobulin |
| Database Links | Reactome: R-HSA-381426Reactome: R-HSA-8957275 |
| Cellular Localisation | Secreted |
| Alternative Antibody Names | Anti-Alpha-Fetoprotein antibodyAnti-Alpha-1-Fetoprotein antibodyAnti-Alpha-Fetoglobulin antibodyAnti-AFP antibodyAnti-HPAFP antibody |
Information sourced from Uniprot.org