| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-Actin filament-associated protein 1 is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: |
1 mg/mL |
| Dilution Range: |
WB 1:500-2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
AFAP1 |
| Gene ID: |
60312 |
| Uniprot ID: |
AFAP1_HUMAN |
| Specificity: |
This antibody detects endogenous levels of AFAP1 at Human, Mouse, Rat |
| Immunogen: |
Synthesized peptide derived from human AFAP1 |
| Post Translational Modifications | Phosphorylated on tyrosine residues by SRC. |
| Function | Can cross-link actin filaments into both network and bundle structures. May modulate changes in actin filament integrity and induce lamellipodia formation. May function as an adapter molecule that links other proteins, such as SRC and PKC to the actin cytoskeleton. Seems to play a role in the development and progression of prostate adenocarcinoma by regulating cell-matrix adhesions and migration in the cancer cells. |
| Protein Name | Actin Filament-Associated Protein 1110 Kda Actin Filament-Associated ProteinAfap-110 |
| Cellular Localisation | CytoplasmCytoskeletonStress Fiber |
| Alternative Antibody Names | Anti-Actin Filament-Associated Protein 1 antibodyAnti-110 Kda Actin Filament-Associated Protein antibodyAnti-Afap-110 antibodyAnti-AFAP1 antibodyAnti-AFAP antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
