| Tissue Specificity | Expressed in osteoblast and visceral fat. |
| Post Translational Modifications | Phosphorylated by MAPK1 in vitro. |
| Function | Isoform 1: As a positive regulator of collagen fibrillogenesis, it is probably involved in the organization and remodeling of the extracellular matrix. Isoform 2: May positively regulate MAP-kinase activity in adipocytes, leading to enhanced adipocyte proliferation and reduced adipocyte differentiation. May also positively regulate NF-kappa-B activity in macrophages by promoting the phosphorylation and subsequent degradation of I-kappa-B-alpha (NFKBIA), leading to enhanced macrophage inflammatory responsiveness. Can act as a transcriptional repressor. |
| Protein Name | Adipocyte Enhancer-Binding Protein 1Ae-Binding Protein 1Aortic Carboxypeptidase-Like Protein |
| Cellular Localisation | Isoform 1: SecretedIsoform 2: CytoplasmNucleus |
| Alternative Antibody Names | Anti-Adipocyte Enhancer-Binding Protein 1 antibodyAnti-Ae-Binding Protein 1 antibodyAnti-Aortic Carboxypeptidase-Like Protein antibodyAnti-AEBP1 antibodyAnti-ACLP antibody |
Information sourced from Uniprot.org
