Anti-ADORA2A antibody (360aa C-Term) (STJ140159)
SPECIFICATIONS
ClonalityPolyclonal
HostGoat
ConjugationUnconjugated
IsotypeIgG
ImmunogenRecombinant peptide derived from within residues 360 aa to the C-terminus of human ADORA2A produced in E. coli.
General Information
| Short Description | Goat polyclonal Adenosine receptor A2a (360aa C-Term) antibody for use in WB, IHC-F and IHC-P in human, rat, mouse, canine and monkey samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC-F/IHC-P |
| Host | Goat |
| Reactivity | Human/Rat/Mouse/Canine/Monkey |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 3 mg/mL |
| Purification | This antibody is epitope-affinity purified from goat antiserum. |
| Dilution Range | WB 1:500-1:2000IHC-F 1:250-1:1000IHC-P 1:250-1:1000 |
| Formulation | PBS, 20% Glycerol and 0.05% Sodium Azide. |
| Storage Instruction | For continuous use, store at 2-8 C for one-two days. For extended storage, store in-20 C freezer. Working dilution samples should be discarded if not used within 12 hours. |
Target Information
| Gene Symbol | ADORA2A |
| Gene ID | 135 |
| Uniprot ID | AA2AR_HUMAN |
| Accession Number | ENSG00000128271 |
| Immunogen | Recombinant peptide derived from within residues 360 aa to the C-terminus of human ADORA2A produced in E. coli. |
| Immunogen Region | 360aa C-Term |
| Immunogen Sequence | YALGLVSGGSAQESQGNTGL ALGLVSGGSAQESQGNTGLP LGLVSGGSAQESQGNTGLPD |
| Specificity | Detects endogenous levels of ADORA2A in brain by Western blot. |
Additional Info
| Post Translational Modifications | Ubiquitinated. Deubiquitinated by USP4.leading to stabilization and expression at the cell surface. |
| Function | Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. |
| Protein Name | Adenosine Receptor A2a |
| Database Links | Reactome: R-HSA-187024Reactome: R-HSA-417973Reactome: R-HSA-418555Reactome: R-HSA-5683826 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane ProteinColocalizes With Gas2l2 At Neuronal Processes |
| Alternative Antibody Names | Anti-Adenosine Receptor A2a antibodyAnti-ADORA2A antibodyAnti-ADORA2 antibody |
Information sourced from Uniprot.org