Anti-ADHFE1 antibody (STJA0004576)

SKU:
STJA0004576
£140.50 - £415.50
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Host: Rabbit
Applications: IHC/ELISA
Reactivity: Human/Mouse/Rat
Note: FOR SCIENTIFIC EDUCATIONAL RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR OTHER MEDICAL APPLICATIONS.
Short Description : Rabbit polyclonal antibody anti-Hydroxyacid-Oxoacid Transhydrogenase-Mitochondrial is suitable for use in Immunohistochemistry and ELISA research applications.
Clonality : Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Purification: Affinity purification
Concentration: 0.2 mg/mL
Dilution Range: IHC 1:50-1:200
Storage Instruction: Store at-20°C for long term, and avoid freeze-thaw cycles.
Gene Symbol: ADHFE1
Gene ID: 137872
Uniprot ID: HOT_HUMAN
Immunogen: Synthetic peptide of human ADHFE1
Tissue Specificity Only expressed in adult liver.
Function Catalyzes the cofactor-independent reversible oxidation of gamma-hydroxybutyrate (GHB) to succinic semialdehyde (SSA) coupled to reduction of 2-ketoglutarate (2-KG) to D-2-hydroxyglutarate (D-2-HG). D,L-3-hydroxyisobutyrate and L-3-hydroxybutyrate (L-3-OHB) are also substrates for HOT with 10-fold lower activities.
Protein Name Hydroxyacid-Oxoacid Transhydrogenase - Mitochondrial
Hot
Alcohol Dehydrogenase Iron-Containing Protein 1
Adhfe1
Fe-Containing Alcohol Dehydrogenase
Database Links Reactome: R-HSA-880009
Cellular Localisation Mitochondrion
Alternative Antibody Names Anti-Hydroxyacid-Oxoacid Transhydrogenase - Mitochondrial antibody
Anti-Hot antibody
Anti-Alcohol Dehydrogenase Iron-Containing Protein 1 antibody
Anti-Adhfe1 antibody
Anti-Fe-Containing Alcohol Dehydrogenase antibody
Anti-ADHFE1 antibody
Anti-HMFT2263 antibody

Information sourced from Uniprot.org

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