| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000 ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | ADGRL4 |
| Gene ID: | 64123 |
| Uniprot ID: | AGRL4_HUMAN |
| Immunogen Region: | 110-406 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 110-406 of human ADGRL4 (NP_071442.2). |
| Immunogen Sequence: | NVNANCHLDNVCIAANINKT LTKIRSIKEPVALLQEVYRN SVTDLSPTDIITYIEILAES SSLLGYKNNTISAKDTLSNS TLTEFVKTVNNFVQRDTFVV WDKLSVNHRRTHLTKLMHTV EQATLRISQSFQKTTEFDTN STDIALKVFFFDSYNMKHIH PHMNMDGDYINIFPKRKAAY DSNGNVAVAFVYYKSIGPLL SSSDNFLLKPQNYDNSEEEE RVISSVISVSMSSNPPTLY |
| Tissue Specificity | Detected in the majority of epithelial cells in tumor and normal tissues. Expressed also in human umbilical vein endothelial cells. |
| Post Translational Modifications | Glycosylated. Proteolytically cleaved into 2 subunits, an extracellular alpha subunit and a seven-transmembrane subunit. |
| Function | Endothelial orphan receptor that acts as a key regulator of angiogenesis. |
| Protein Name | Adhesion G Protein-Coupled Receptor L4 Egf - Latrophilin And Seven Transmembrane Domain-Containing Protein 1 Egf-Tm7-Latrophilin-Related Protein Etl Protein |
| Cellular Localisation | Cell Membrane Multi-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Adhesion G Protein-Coupled Receptor L4 antibody Anti-Egf - Latrophilin And Seven Transmembrane Domain-Containing Protein 1 antibody Anti-Egf-Tm7-Latrophilin-Related Protein antibody Anti-Etl Protein antibody Anti-ADGRL4 antibody Anti-ELTD1 antibody Anti-ETL antibody Anti-UNQ202 antibody Anti-PRO228 antibody |
Information sourced from Uniprot.org