| Host: | Rabbit |
| Applications: | WB/ELISA/IHC |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-Adhesion G protein-coupled receptor L1 (561-610 aa) is suitable for use in Western Blot, ELISA and Immunohistochemistry research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-2000IHC-P 1:50-300ELISA 2000-20000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | ADGRL1 |
| Gene ID: | 22859 |
| Uniprot ID: | AGRL1_HUMAN |
| Immunogen Region: | 561-610 aa |
| Specificity: | Latrophilin-1 Polyclonal Antibody detects endogenous levels of Latrophilin-1 protein. |
| Immunogen: | The antiserum was produced against synthesized peptide derived from the human LPHN1 at the amino acid range 561-610 |
| Function | Calcium-independent receptor of high affinity for alpha-latrotoxin, an excitatory neurotoxin present in black widow spider venom which triggers massive exocytosis from neurons and neuroendocrine cells. Receptor for TENM2 that mediates heterophilic synaptic cell-cell contact and postsynaptic specialization. Receptor probably implicated in the regulation of exocytosis. |
| Protein Name | Adhesion G Protein-Coupled Receptor L1Calcium-Independent Alpha-Latrotoxin Receptor 1Cirl-1Latrophilin-1Lectomedin-2 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane ProteinCell ProjectionAxonGrowth ConeSynapsePresynaptic Cell MembraneSynaptosomeColocalizes With Tenm2 On The Cell SurfaceAcross Intercellular Junctions And On Nerve Terminals Near Synaptic Clefts |
| Alternative Antibody Names | Anti-Adhesion G Protein-Coupled Receptor L1 antibodyAnti-Calcium-Independent Alpha-Latrotoxin Receptor 1 antibodyAnti-Cirl-1 antibodyAnti-Latrophilin-1 antibodyAnti-Lectomedin-2 antibodyAnti-ADGRL1 antibodyAnti-KIAA0821 antibodyAnti-LEC2 antibodyAnti-LPHN1 antibody |
Information sourced from Uniprot.org