| Post Translational Modifications | Autoproteolytically processed at the GPS region of the GAIN-B domain.this cleavage modulates receptor activity. N-glycosylated. |
| Function | Orphan adhesion G-protein coupled receptor (aGPCR). Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of downstream effectors, such as adenylate cyclase. ADGRG4 is coupled to G(s) G proteins and mediates activation of adenylate cyclase activity. May be act as sensor of mechanical forces. |
| Protein Name | Adhesion G-Protein Coupled Receptor G4G-Protein Coupled Receptor 112 Cleaved Into - Adhesion G-Protein Coupled Receptor G4 - N-Terminal FragmentAdgrg4 N-Terminal Fragment - Adhesion G-Protein Coupled Receptor G4 - C-Terminal FragmentAdgrg4 C-Terminal Fragment |
| Database Links | |
| Cellular Localisation | MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Adhesion G-Protein Coupled Receptor G4 antibodyAnti-G-Protein Coupled Receptor 112 Cleaved Into - Adhesion G-Protein Coupled Receptor G4 - N-Terminal Fragment antibodyAnti-Adgrg4 N-Terminal Fragment - Adhesion G-Protein Coupled Receptor G4 - C-Terminal Fragment antibodyAnti-Adgrg4 C-Terminal Fragment antibodyAnti-ADGRG4 antibodyAnti-GPR112 antibody |
Information sourced from Uniprot.org
