| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-ADGRB3 (70-280) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
ADGRB3 |
| Gene ID: |
577 |
| Uniprot ID: |
AGRB3_HUMAN |
| Immunogen Region: |
70-280 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 70-280 of human ADGRB3 (NP_001695.1). |
| Immunogen Sequence: |
YLKFSKKDLSCSNFSLLAYQ FDHFSHEKIKDLLRKNHSIM QLCNSKNAFVFLQYDKNFIQ IRRVFPTNFPGLQKKGEEDQ KSFFEFLVLNKVSPSQFGCH VLCTWLESCLKSENGRTESC GIMYTKCTCPQHLGEWGIDD QSLILLNNVVLPLNEQTEGC LTQELQTTQVCNLTREAKRP PKEEFGMMGDHTIKSQRPRS VHEKRVPQEQA |
| Tissue Specificity | Strongly expressed in brain. Also detected in heart. Reduced expression in some glioblastoma cell lines. |
| Post Translational Modifications | The endogenous protein is proteolytically cleaved into 2 subunits, an extracellular subunit and a seven-transmembrane subunit. |
| Function | Receptor that plays a role in the regulation of synaptogenesis and dendritic spine formation at least partly via interaction with ELMO1 and RAC1 activity. Promotes myoblast fusion through ELMO/DOCK1. |
| Protein Name | Adhesion G Protein-Coupled Receptor B3Brain-Specific Angiogenesis Inhibitor 3 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Adhesion G Protein-Coupled Receptor B3 antibodyAnti-Brain-Specific Angiogenesis Inhibitor 3 antibodyAnti-ADGRB3 antibodyAnti-BAI3 antibodyAnti-KIAA0550 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
