| Tissue Specificity | Expressed primarily in adult skeletal muscle. |
| Post Translational Modifications | C-, N- and O-glycosylated. O-fucosylated by POFUT2 on a serine or a threonine residue found within the consensus sequence C1-X(2)-(S/T)-C2-G of the TSP type-1 repeat domains where C1 and C2 are the first and second cysteine residue of the repeat, respectively. Fucosylated repeats can then be further glycosylated by the addition of a beta-1,3-glucose residue by the glucosyltransferase, B3GALTL. Fucosylation mediates the efficient secretion of ADAMTSL1. Can also be C-glycosylated with one or two mannose molecules on tryptophan residues within the consensus sequence W-X-X-W of the TPRs, and N-glycosylated. These other glycosylations can also facilitate secretion. Disulfide bonds are present. |
| Protein Name | Adamts-Like Protein 1Adamtsl-1Punctin-1 |
| Database Links | Reactome: R-HSA-5083635Reactome: R-HSA-5173214 |
| Cellular Localisation | SecretedExtracellular SpaceExtracellular Matrix |
| Alternative Antibody Names | Anti-Adamts-Like Protein 1 antibodyAnti-Adamtsl-1 antibodyAnti-Punctin-1 antibodyAnti-ADAMTSL1 antibodyAnti-ADAMTSR1 antibodyAnti-C9orf94 antibodyAnti-UNQ528 antibodyAnti-PRO1071 antibody |
Information sourced from Uniprot.org
