| Host: | Rabbit |
| Applications: | WB/IHC-P/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000IHC-P:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | ACOT2 |
| Gene ID: | 10965 |
| Uniprot ID: | ACOT2_HUMAN |
| Immunogen Region: | 222-483 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 222-483 of human ACOT2 (NP_006812.3). |
| Immunogen Sequence: | IVDMFGTGGGLLEYRASLLA GKGFAVMALAYYNYEDLPKT METLHLEYFEEAMNYLLSHP EVKGPGVGLLGISKGGELCL SMASFLKGITAAVVINGSVA NVGGTLHYKGETLPPVGVNR NRIKVTKDGYADIVDVLNSP LEGPDQKSFIPVERAESTFL FLVGQDDHNWKSEFYANEAC KRLQAHGRRKPQIICYPETG HYIEPPYFPLCRASLHALVG SPIIWGGEPRAHAMAQVDA |
| Tissue Specificity | Strongest expression in heart, liver, muscle and kidney. Weak in placenta and pancreas. |
| Function | Catalyzes the hydrolysis of acyl-CoAs into free fatty acids and coenzyme A (CoASH), regulating their respective intracellular levels. Displays higher activity toward long chain acyl CoAs (C14-C20). The enzyme is involved in enhancing the hepatic fatty acid oxidation in mitochondria. |
| Protein Name | Acyl-Coenzyme A Thioesterase 2 - MitochondrialAcyl-Coa Thioesterase 2Acyl-Coenzyme A Thioester Hydrolase 2aCte-IaLong-Chain Acyl-Coa Thioesterase 2Zap128 |
| Database Links | Reactome: R-HSA-77289Reactome: R-HSA-9033241Reactome: R-HSA-9837999 |
| Cellular Localisation | Mitochondrion |
| Alternative Antibody Names | Anti-Acyl-Coenzyme A Thioesterase 2 - Mitochondrial antibodyAnti-Acyl-Coa Thioesterase 2 antibodyAnti-Acyl-Coenzyme A Thioester Hydrolase 2a antibodyAnti-Cte-Ia antibodyAnti-Long-Chain Acyl-Coa Thioesterase 2 antibodyAnti-Zap128 antibodyAnti-ACOT2 antibodyAnti-PTE2 antibodyAnti-PTE2A antibody |
Information sourced from Uniprot.org