• Western blot analysis of lysates from A549 cells, primary antibody was diluted at 1:1000, 4°C over night

Anti-ACADL antibody (258-308 aa) (STJ194948)

SKU:
STJ194948

Current Stock:
Host: Rabbit
Applications: WB
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Long-chain specific acyl-CoA dehydrogenase, mitochondrial (258-308 aa) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: ACADL
Gene ID: 33
Uniprot ID: ACADL_HUMAN
Immunogen Region: 258-308 aa
Specificity: This antibody detects endogenous levels of ACADL at Human/Mouse/Rat
Immunogen: Synthesized peptide derived from the human ACADL at the amino acid range 258-308
Function Long-chain specific acyl-CoA dehydrogenase is one of the acyl-CoA dehydrogenases that catalyze the first step of mitochondrial fatty acid beta-oxidation, an aerobic process breaking down fatty acids into acetyl-CoA and allowing the production of energy from fats. The first step of fatty acid beta-oxidation consists in the removal of one hydrogen from C-2 and C-3 of the straight-chain fatty acyl-CoA thioester, resulting in the formation of trans-2-enoyl-CoA. Among the different mitochondrial acyl-CoA dehydrogenases, long-chain specific acyl-CoA dehydrogenase can act on saturated and unsaturated acyl-CoAs with 6 to 24 carbons with a preference for 8 to 18 carbons long primary chains.
Protein Name Long-Chain Specific Acyl-Coa Dehydrogenase - Mitochondrial
Lcad
Database Links Reactome: R-HSA-77285
Reactome: R-HSA-77288
Reactome: R-HSA-77310
Cellular Localisation Mitochondrion Matrix
Alternative Antibody Names Anti-Long-Chain Specific Acyl-Coa Dehydrogenase - Mitochondrial antibody
Anti-Lcad antibody
Anti-ACADL antibody

Information sourced from Uniprot.org

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