| Function | Lipase that preferentially hydrolysis medium-chain saturated monoacylglycerols including 2-arachidonoylglycerol. Through 2-arachidonoylglycerol degradation may regulate endocannabinoid signaling pathways. Also has a lysophosphatidyl lipase activity with a preference for lysophosphatidylglycerol among other lysophospholipids. Also able to degrade bis(monoacylglycero)phosphate (BMP) and constitutes the major enzyme for BMP catabolism. BMP, also known as lysobisphosphatidic acid, is enriched in late endosomes and lysosomes and plays a key role in the formation of intraluminal vesicles and in lipid sorting. |
| Protein Name | Monoacylglycerol Lipase Abhd62-Arachidonoylglycerol HydrolaseAbhydrolase Domain-Containing Protein 6 |
| Database Links | Reactome: R-MMU-426048 |
| Cellular Localisation | Late Endosome MembraneSingle-Pass Type Ii Membrane ProteinLysosome MembraneMitochondrion Membrane |
| Alternative Antibody Names | Anti-Monoacylglycerol Lipase Abhd6 antibodyAnti-2-Arachidonoylglycerol Hydrolase antibodyAnti-Abhydrolase Domain-Containing Protein 6 antibodyAnti-Abhd6 antibody |
Information sourced from Uniprot.org
