| Short Description : | Rabbit polyclonal ABHD4 (223-342) antibody for use in WB, IF, ICC and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | WB/IF/ICC/ELISA |
| Host: | Rabbit |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | Lot specific |
| Purification: | Affinity purification |
| Dilution Range: | WB:1:500-1:2000IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | ABHD4 |
| Gene ID: | 63874 |
| Uniprot ID: | ABHD4_HUMAN |
| Immunogen Region: | 223-342 |
| Immunogen Sequence: | PDFKRKFADFFEDDTISEYI YHCNAQNPSGETAFKAMMES FGWARRPMLERIHLIRKDVP ITMIYGSDTWIDTSTGKKVK MQRPDSYVRDMEIKGASHHV YADQPHIFNAVVEEICDSVD |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 223-342 of human ABHD4 (NP_071343.2). |
| Function | Lysophospholipase selective for N-acyl phosphatidylethanolamine (NAPE). Contributes to the biosynthesis of N-acyl ethanolamines, including the endocannabinoid anandamide by hydrolyzing the sn-1 and sn-2 acyl chains from N-acyl phosphatidylethanolamine (NAPE) generating glycerophospho-N-acyl ethanolamine (GP-NAE), an intermediate for N-acyl ethanolamine biosynthesis. Hydrolyzes substrates bearing saturated, monounsaturated, polyunsaturated N-acyl chains. Shows no significant activity towards other lysophospholipids, including lysophosphatidylcholine, lysophosphatidylethanolamine and lysophosphatidylserine. |
| Protein Name | (Lyso-N-Acylphosphatidylethanolamine LipaseAlpha/Beta Hydrolase Domain-Containing Protein 4Abhydrolase Domain-Containing Protein 4Alpha/Beta-Hydrolase 4 |
| Database Links | Reactome: R-HSA-1482839 |
| Cellular Localisation | |
| Alternative Antibody Names | Anti-(Lyso-N-Acylphosphatidylethanolamine Lipase antibodyAnti-Alpha/Beta Hydrolase Domain-Containing Protein 4 antibodyAnti-Abhydrolase Domain-Containing Protein 4 antibodyAnti-Alpha/Beta-Hydrolase 4 antibodyAnti-ABHD4 antibody |
Information sourced from Uniprot.org
