| Short Description : | Rabbit polyclonal anti-ATP-binding cassette sub-family G member 5 (250-330 aa) for use in WB, IF and ELISA in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | WB/IF/ELISA |
| Host: | Rabbit |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | 1 mg/mL |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range: | WB 1:500-1:2000ELISA 1:5000IF 1:100-300 |
| Formulation: | Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | ABCG5 |
| Gene ID: | 64240 |
| Uniprot ID: | ABCG5_HUMAN |
| Immunogen: | Synthesized peptide derived from the human protein at the amino acid range 250-330 |
| Immunogen Region: | 250-330 aa |
| Specificity: | ABCG5 Polyclonal Antibody detects endogenous levels of protein. |
| Post Translational Modifications | N-glycosylated. |
| Function | ABCG5 and ABCG8 form an obligate heterodimer that mediates Mg(2+)- and ATP-dependent sterol transport across the cell membrane. Plays an essential role in the selective transport of dietary plant sterols and cholesterol in and out of the enterocytes and in the selective sterol excretion by the liver into bile. Required for normal sterol homeostasis. The heterodimer with ABCG8 has ATPase activity. |
| Protein Name | Atp-Binding Cassette Sub-Family G Member 5Sterolin-1 |
| Database Links | Reactome: R-HSA-1369062Reactome: R-HSA-5679090Reactome: R-HSA-5679096Reactome: R-HSA-9029569 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane ProteinApical Cell Membrane |
| Alternative Antibody Names | Anti-Atp-Binding Cassette Sub-Family G Member 5 antibodyAnti-Sterolin-1 antibodyAnti-ABCG5 antibody |
Information sourced from Uniprot.org
