| Host: |
Goat |
| Applications: |
Pep-ELISA/FC/IHC |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Goat polyclonal antibody anti-ABCD3 (Internal) is suitable for use in ELISA, Flow Cytometry and Immunohistochemistry research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Purification: |
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Concentration: |
0.5 mg/mL |
| Dilution Range: |
WB-0.2-0.6 µg/mlIHC-2.5-3.8µg/mlELISA-antibody detection limit dilution 1:16000. |
| Storage Instruction: |
Store at-20°C on receipt and minimise freeze-thaw cycles. |
| Gene Symbol: |
ABCD3 |
| Gene ID: |
5825 |
| Uniprot ID: |
ABCD3_HUMAN |
| Immunogen Region: |
Internal |
| Accession Number: |
NP_002849.1 |
| Specificity: |
This antibody is expected to recognize one isoform (NP_002849.1) only. |
| Immunogen Sequence: |
PDGREDQKRKGISD |
| Function | Broad substrate specificity ATP-dependent transporter of the ATP-binding cassette (ABC) family that catalyzes the transport of long-chain fatty acids (LCFA)-CoA, dicarboxylic acids-CoA, long-branched-chain fatty acids-CoA and bile acids from the cytosol to the peroxisome lumen for beta-oxydation. Has fatty acyl-CoA thioesterase and ATPase activities. Probably hydrolyzes fatty acyl-CoAs into free fatty acids prior to their ATP-dependent transport into peroxisomes. Thus, play a role in regulation of LCFAs and energy metabolism namely, in the degradation and biosynthesis of fatty acids by beta-oxidation. |
| Protein Name | Atp-Binding Cassette Sub-Family D Member 370 Kda Peroxisomal Membrane ProteinPmp70 |
| Database Links | Reactome: R-HSA-1369062Reactome: R-HSA-8980692Reactome: R-HSA-9013106Reactome: R-HSA-9603798 |
| Cellular Localisation | Peroxisome MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Atp-Binding Cassette Sub-Family D Member 3 antibodyAnti-70 Kda Peroxisomal Membrane Protein antibodyAnti-Pmp70 antibodyAnti-ABCD3 antibodyAnti-PMP70 antibodyAnti-PXMP1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
