Anti-ABCB5 antibody [11A2] (STJ96976)
SPECIFICATIONS
ClonalityMonoclonal
HostMouse
ConjugationUnconjugated
IsotypeIgG1
ImmunogenSynthetic Peptide of ABCB5
General Information
| Short Description | Mouse monoclonal anti-ATP-binding cassette sub-family B member 5 for use in WB, IHC and IF in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC/IF |
| Host | Mouse |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | 11A2 |
| Isotype | IgG1 |
| Conjugation | Unconjugated |
| Purification | The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen. |
| Dilution Range | WB 1:2000IF 1:200IHC 1:50-300 |
| Formulation | Liquid in PBS pH7.4, 0.5% BSA, 0.02% Sodium Azide and 50% Glycerol. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | ABCB5 |
| Gene ID | 340273 |
| Uniprot ID | ABCB5_HUMAN |
| Immunogen | Synthetic Peptide of ABCB5 |
| Specificity | The antibody detects endogenous ABCB5 proteins. |
Additional Info
| Function | Energy-dependent efflux transporter responsible for decreased drug accumulation in multidrug-resistant cells. Specifically present in limbal stem cells, where it plays a key role in corneal development and repair. |
| Protein Name | Atp-Binding Cassette Sub-Family B Member 5Abcb5 P-GpP-Glycoprotein Abcb5 |
| Database Links | Reactome: R-HSA-382556 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Atp-Binding Cassette Sub-Family B Member 5 antibodyAnti-Abcb5 P-Gp antibodyAnti-P-Glycoprotein Abcb5 antibodyAnti-ABCB5 antibody |
Information sourced from Uniprot.org