Anti-5HT1B antibody (160-260) {Biotin} (STJ500004)


Current Stock:
Host: Rabbit
Applications: ELISA, IP, WB
Reactivity: Human, Mouse, Rat
Short Description: Rabbit polyclonal antibody anti-5HT1B (160-260) is suitable for use in ELISA, Immunoprecipitation and Western Blot research applications.
Clonality: Polyclonal
Conjugation: Biotin
Isotype: IgG
Purification: Affinity Purified
Concentration: 0.5-1.5 µg/µl
Dilution Range: WB: 1:2, 500-1:5, 000
DB: 1:50, 000
ELISA: 1:50, 000
IP: 1:200
Storage Instruction: Store at-20°C for long term storage. Avoid freeze-thaw cycles.
Gene Symbol: Htr1b
Gene ID: 15551
Uniprot ID: 5HT1B_MOUSE
Immunogen Region: 160-260
Immunogen: Synthetic peptide taken within amino acid region 160-260 on rat 5HT1B.
Tissue Specificity Predominantly expressed in striatum and Purkinje cells.
Post Translational Modifications Phosphorylated. Palmitoylated.
Function G-protein coupled receptor for 5-hydroxytryptamine (serotonin). Also functions as a receptor for various alkaloids and psychoactive substances. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling inhibits adenylate cyclase activity. Arrestin family members inhibit signaling via G proteins and mediate activation of alternative signaling pathways. Regulates the release of 5-hydroxytryptamine, dopamine and acetylcholine in the brain, and thereby affects neural activity, nociceptive processing, pain perception, mood and behavior. Besides, plays a role in vasoconstriction of cerebral arteries.
Protein Name 5-Hydroxytryptamine Receptor 1b
Serotonin Receptor 1b
Database Links Reactome: R-MMU-390666
Reactome: R-MMU-418594
Cellular Localisation Cell Membrane
Multi-Pass Membrane Protein
Alternative Antibody Names Anti-5-Hydroxytryptamine Receptor 1b antibody
Anti-5-Ht-1b antibody
Anti-5-Ht1b antibody
Anti-Serotonin Receptor 1b antibody
Anti-Htr1b antibody
Anti-5ht1b antibody

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