| Applications: | WB |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: | ADCY9 Positive Control for STJ502079 is synthetically produced from the sequence and is suitable for use in western blot applications. |
| Formulation: | Provided as 100 uL ready-to-use, in SDS-PAGE sample buffer (Laemelli's buffer) containing Tris, pH 6.8, 1 % SDS, Glycerol and Bromophenolblue blue as tracking dye. The sample is reduced by adding 2% beta mercaptoethanol. The protein concentration is |
| Dilution Range: | WB: 1:500 |
| Storage Instruction: | Store at-20°C for long term storage. Avoid freeze-thaw cycles. |
| Gene Symbol: | ADCY9 |
| Gene ID: | 115 |
| Uniprot ID: | ADCY9_HUMAN |
| Specificity: | This is positive control is recommended for use in combination with ADCY9 antibody STJ502079. |
| Tissue Specificity | Detected in skeletal muscle, pancreas, lung, heart, kidney, liver, brain and placenta. Expressed in multiple cells of the lung, with expression highest in airway smooth muscle. |
| Function | Adenylyl cyclase that catalyzes the formation of the signaling molecule cAMP in response to activation of G protein-coupled receptors. Contributes to signaling cascades activated by CRH (corticotropin-releasing factor), corticosteroids and beta-adrenergic receptors. |
| Peptide Name | Adenylate Cyclase Type 9Atp Pyrophosphate-Lyase 9Adenylate Cyclase Type IxAcixAdenylyl Cyclase 9Ac9 |
| Database Links | Reactome: R-HSA-163359Reactome: R-HSA-163615Reactome: R-HSA-164378Reactome: R-HSA-170660Reactome: R-HSA-170670Reactome: R-HSA-418555Reactome: R-HSA-418594Reactome: R-HSA-418597Reactome: R-HSA-432040Reactome: R-HSA-5610787Reactome: R-HSA-9634597Reactome: R-HSA-9660821Reactome: R-HSA-9664323 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
| Alternative Peptide Names | Adenylate Cyclase Type 9 proteinAtp Pyrophosphate-Lyase 9 proteinAdenylate Cyclase Type Ix proteinAcix proteinAdenylyl Cyclase 9 proteinAc9 proteinADCY9 proteinKIAA0520 protein |
Information sourced from Uniprot.org
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