| Applications: |
WB |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
VKORC1 Positive Control for STJ503490 is synthetically produced from the sequence and is suitable for use in western blot applications. |
| Formulation: |
Provided as 100 uL ready-to-use, in SDS-PAGE sample buffer (Laemelli's buffer) containing Tris, pH 6.8, 1 % SDS, Glycerol and Bromophenolblue blue as tracking dye. The sample is reduced by adding 2% beta mercaptoethanol. The protein concentration is |
| Dilution Range: |
WB: 1:500 |
| Storage Instruction: |
Store at-20°C for long term storage. Avoid freeze-thaw cycles. |
| Gene Symbol: |
Vkorc1 |
| Gene ID: |
309004 |
| Uniprot ID: |
VKOR1_RAT |
| Specificity: |
This is positive control is recommended for use in combination with VKORC1 antibody STJ503490. |
| Tissue Specificity | Highly expressed in liver. Detected at lower levels in lung, kidney and testis. |
| Function | Involved in vitamin K metabolism. Catalytic subunit of the vitamin K epoxide reductase (VKOR) complex which reduces inactive vitamin K 2,3-epoxide to active vitamin K. Vitamin K is required for the gamma-carboxylation of various proteins, including clotting factors, and is required for normal blood coagulation, but also for normal bone development. |
| Peptide Name | Vitamin K Epoxide Reductase Complex Subunit 1Vitamin K1 2 -3-Epoxide Reductase Subunit 1 |
| Database Links | Reactome: R-RNO-6806664 |
| Cellular Localisation | Endoplasmic Reticulum MembraneMulti-Pass Membrane Protein |
| Alternative Peptide Names | Vitamin K Epoxide Reductase Complex Subunit 1 proteinVitamin K1 2 -3-Epoxide Reductase Subunit 1 proteinVkorc1 protein |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
