VKORC1 Positive Control for STJ503490 peptide (STJ505251)

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STJ505251-5
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Applications: WB
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : VKORC1 Positive Control for STJ503490 is synthetically produced from the sequence and is suitable for use in western blot applications.
Formulation: Provided as 100 uL ready-to-use, in SDS-PAGE sample buffer (Laemelli's buffer) containing Tris, pH 6.8, 1 % SDS, Glycerol and Bromophenolblue blue as tracking dye. The sample is reduced by adding 2% beta mercaptoethanol. The protein concentration is
Dilution Range: WB: 1:500
Storage Instruction: Store at-20°C for long term storage. Avoid freeze-thaw cycles.
Gene Symbol: Vkorc1
Gene ID: 309004
Uniprot ID: VKOR1_RAT
Specificity: This is positive control is recommended for use in combination with VKORC1 antibody STJ503490.
Tissue Specificity Highly expressed in liver. Detected at lower levels in lung, kidney and testis.
Function Involved in vitamin K metabolism. Catalytic subunit of the vitamin K epoxide reductase (VKOR) complex which reduces inactive vitamin K 2,3-epoxide to active vitamin K. Vitamin K is required for the gamma-carboxylation of various proteins, including clotting factors, and is required for normal blood coagulation, but also for normal bone development.
Peptide Name Vitamin K Epoxide Reductase Complex Subunit 1
Vitamin K1 2 -3-Epoxide Reductase Subunit 1
Database Links Reactome: R-RNO-6806664
Cellular Localisation Endoplasmic Reticulum Membrane
Multi-Pass Membrane Protein
Alternative Peptide Names Vitamin K Epoxide Reductase Complex Subunit 1 protein
Vitamin K1 2 -3-Epoxide Reductase Subunit 1 protein
Vkorc1 protein

Information sourced from Uniprot.org

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