TNK1 Positive Control for STJ506145 peptide (STJ505856)

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STJ505856-5
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Applications: WB
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : TNK1 Positive Control for STJ506145 is synthetically produced from the sequence and is suitable for use in western blot applications.
Formulation: Provided as 100 uL ready-to-use, in SDS-PAGE sample buffer (Laemelli's buffer) containing Tris, pH 6.8, 1 % SDS, Glycerol and Bromophenolblue blue as tracking dye. The sample is reduced by adding 2% beta mercaptoethanol. The protein concentration is
Storage Instruction: Store at-20°C for long term storage. Avoid freeze-thaw cycles.
Gene Symbol: TNK1
Gene ID: 8711
Uniprot ID: TNK1_HUMAN
Specificity: This is positive control is recommended for use in combination with TNK1 antibody STJ506145.
Tissue Specificity Expressed in all umbilical cord blood, bone marrow and adult blood cell sub-populations and in several leukemia cell lines. Highly expressed in fetal blood, brain, lung, liver and kidney. Detected at lower levels in adult prostate, testis, ovary, small intestine and colon. Not expressed in adult lung, liver, kidney or brain.
Post Translational Modifications Autophosphorylated on tyrosine residues.
Function Involved in negative regulation of cell growth. Has tumor suppressor properties. Plays a negative regulatory role in the Ras-MAPK pathway. May function in signaling pathways utilized broadly during fetal development and more selectively in adult tissues and in cells of the lymphohematopoietic system. Could specifically be involved in phospholipid signal transduction.
Peptide Name Non-Receptor Tyrosine-Protein Kinase Tnk1
Cd38 Negative Kinase 1
Cellular Localisation Cytoplasm
Membrane
Peripheral Membrane Protein
Alternative Peptide Names Non-Receptor Tyrosine-Protein Kinase Tnk1 protein
Cd38 Negative Kinase 1 protein
TNK1 protein

Information sourced from Uniprot.org

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