TLR12 Positive Control for STJ503292 peptide (STJ505212)
SPECIFICATIONS
General Information
| Short Description | TLR12 Positive Control for STJ503292 is synthetically produced from the sequence and is suitable for use in western blot applications. |
| Applications | WB |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Dilution Range | WB: 1:500 |
| Formulation | Provided as 100 uL ready-to-use, in SDS-PAGE sample buffer (Laemelli's buffer) containing Tris, pH 6.8, 1 % SDS, Glycerol and Bromophenolblue blue as tracking dye. The sample is reduced by adding 2% beta mercaptoethanol. The protein concentration is |
| Storage Instruction | Store at-20°C for long term storage. Avoid freeze-thaw cycles. |
Target Information
| Gene Symbol | Tlr12 |
| Gene ID | 384059 |
| Uniprot ID | TLR12_MOUSE |
| Specificity | This is positive control is recommended for use in combination with TLR12 antibody STJ503292. |
Additional Info
| Tissue Specificity | Macrophages, liver, kidney and bladder epithelial cells. |
| Function | Participates in the innate immune response to microbial agents. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Plays a role in preventing infection of internal organs of the urogenital system. |
| Peptide Name | Toll-Like Receptor 12Toll-Like Receptor 11 |
| Cellular Localisation | MembraneSingle-Pass Type I Membrane Protein |
| Alternative Peptide Names | Toll-Like Receptor 12 proteinToll-Like Receptor 11 proteinTlr12 proteinGm1365 proteinTlr11 protein |
Information sourced from Uniprot.org