| Applications: | Immunodepletion/Immunocompetition |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | TdT Blocking Peptide is synthetically produced from the 459-509 sequence and is suitable for use in western blot applications. |
| Formulation: | Liquid form at 2.5mg/ml concentration in PBS. Up to 5% DMSO can be added. Orders with >1mg can be supplied in lyophilized powder form, or in buffer of choice. |
| Storage Instruction: | Store at-20°C for long term storage. Avoid freeze-thaw cycles. |
| Gene Symbol: | DNTT |
| Gene ID: | 1791 |
| Uniprot ID: | TDT_HUMAN |
| Immunogen Region: | 459-509 |
| Immunogen: | Synthetic peptide taken within amino acid region 459-509 on human Terminal deoxynucleotidyltransferase protein. |
| Function | Template-independent DNA polymerase which catalyzes the random addition of deoxynucleoside 5'-triphosphate to the 3'-end of a DNA initiator. One of the in vivo functions of this enzyme is the addition of nucleotides at the junction (N region) of rearranged Ig heavy chain and T-cell receptor gene segments during the maturation of B- and T-cells. |
| Peptide Name | Dna NucleotidylexotransferaseTerminal Addition EnzymeTerminal DeoxynucleotidyltransferaseTerminal Transferase |
| Cellular Localisation | Nucleus |
| Alternative Peptide Names | Dna Nucleotidylexotransferase proteinTerminal Addition Enzyme proteinTerminal Deoxynucleotidyltransferase proteinTerminal Transferase proteinDNTT proteinTDT protein |
Information sourced from Uniprot.org