| Tissue Specificity | Expressed in trophoblast cells of placental villi. |
| Post Translational Modifications | Palmitoylated. Probably palmitoylated by ZDHHC3 and ZDHHC7. |
| Function | GTPase activator for the Rho-type GTPases. As a GCM1 downstream effector, it is involved in placental development and positively regulates trophoblast cells migration. It regulates cytoskeletal remodeling by controlling the activity of Rho GTPases including RHOA, CDC42 and RAC1. |
| Peptide Name | Rho Gtpase-Activating Protein Syde1Synapse Defective Protein 1 Homolog 1Protein Syd-1 Homolog 1 |
| Database Links | Reactome: R-HSA-9013148Reactome: R-HSA-9013404Reactome: R-HSA-9013406Reactome: R-HSA-9013409Reactome: R-HSA-9013423Reactome: R-HSA-9035034 |
| Alternative Peptide Names | Rho Gtpase-Activating Protein Syde1 proteinSynapse Defective Protein 1 Homolog 1 proteinProtein Syd-1 Homolog 1 proteinSYDE1 protein |
Information sourced from Uniprot.org