S100 beta Blocking Peptide peptide (STJ504878)

SKU:
STJ504878-250

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Applications: Immunodepletion/Immunocompetition
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: S100 beta Blocking Peptide is synthetically produced from the N-Term sequence and is suitable for use in western blot applications.
Formulation: Liquid form at 2.5mg/ml concentration in PBS. Up to 5% DMSO can be added. Orders with >1mg can be supplied in lyophilized powder form, or in buffer of choice.
Storage Instruction: Store at-20°C for long term storage. Avoid freeze-thaw cycles.
Gene Symbol: S100P
Gene ID: 6286
Uniprot ID: S100P_HUMAN
Immunogen Region: N-Term
Immunogen: N-epitope synthetic peptide corresponding to unique amino acid sequences on human S100 protein.
Tissue Specificity Detected in all of the tissues except brain, testis and small intestine, expression level is higher in placenta, heart, lung, skeletal muscle, spleen and leukocyte. Up-regulated in various pancreatic ductal adenocarcinomas and pancreatic intraepithelial neoplasias.
Function May function as calcium sensor and contribute to cellular calcium signaling. In a calcium-dependent manner, functions by interacting with other proteins, such as EZR and PPP5C, and indirectly plays a role in physiological processes like the formation of microvilli in epithelial cells. May stimulate cell proliferation in an autocrine manner via activation of the receptor for activated glycation end products (RAGE).
Peptide Name Protein S100-P
Migration-Inducing Gene 9 Protein
Mig9
Protein S100-E
S100 Calcium-Binding Protein P
Database Links Reactome: R-HSA-6798695
Cellular Localisation Nucleus
Cytoplasm
Cell Projection
Microvillus Membrane
Colocalizes With S100pbp In The Nucleus
Colocolizes With Ezr In The Microvilli In A Calcium-Dependent Manner
Alternative Peptide Names Protein S100-P protein
Migration-Inducing Gene 9 Protein protein
Mig9 protein
Protein S100-E protein
S100 Calcium-Binding Protein P protein
S100P protein
S100E protein

Information sourced from Uniprot.org

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