RNase 7 protein (STJP000162)

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STJP000162
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Host: CHO cells
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : RNase 7-protein was developed from cho cells. For use in research applications.
Formulation: 10 mM Na-acetate, pH 5.0; 150 mM NaCl
Purification: Purified by affinity chromatography and gel-filtration from serum-free CHO growth media.
Concentration: 1.9 mg/ml
Storage Instruction: Store at-70°C upon receipt. Recommended to aliquot into smaller quantities. Avoid repeated freeze-thaw cycles.
Gene Symbol: RNASE7
Gene ID: 84659
Uniprot ID: RNAS7_HUMAN
Function Exhibits a potent RNase activity. Has broad-spectrum antimicrobial activity against many pathogenic microorganisms including uropathogenic E.coli (UPEC), and remarkably potent activity (lethal dose of 90% < 30 nM) against a vancomycin resistant Enterococcus faecium. Causes loss of bacterial membrane integrity. Probably contributes to urinary tract sterility. Bactericidal activity is independent of RNase activity.
Protein Name Ribonuclease 7
Rnase 7
Skin-Derived Antimicrobial Protein 2
Sap-2
Database Links Reactome: R-HSA-6803157
Cellular Localisation Secreted
Detected In Urine
Alternative Protein Names Ribonuclease 7 protein
Rnase 7 protein
Skin-Derived Antimicrobial Protein 2 protein
Sap-2 protein
RNASE7 protein
UNQ2516 protein
PRO6006 protein

Information sourced from Uniprot.org

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