Rat PXR (Pregnane X Receptor) Sandwich ELISA Kit Ready-To-Use Kit (STJE0018170)

Rat PXR (Pregnane X Receptor) Sandwich ELISA Kit Ready-To-Use Kit (STJE0018170)

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STJE0018170
£518.50 - £712.50
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Applications: ELISA
Reactivity: Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Sensitivity: 0.113ng/mL
Detection Limit: 0.312-20ng/mL
Short Description : This PXR Sandwich ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in rat tissue homogenates, cell lysates or other biological fluids..
Storage Instruction: The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time: 3 hrs
Gene Symbol: Nr1i2
Gene ID: 84385
Uniprot ID: NR1I2_RAT
Immunogen Region: Ready-To-Use
Sample Type: tissue homogenates, cell lysates or other biological fluids.
Tissue Specificity
Post Translational Modifications
Function Nuclear receptor that binds and is activated by a variety of endogenous and xenobiotic compounds. Transcription factor that activates the transcription of multiple genes involved in the metabolism and secretion of potentially harmful xenobiotics, endogenous compounds and drugs. Response to specific ligands is species-specific, due to differences in the ligand-binding domain. Activated by naturally occurring steroids, such as pregnenolone and progesterone. Binds to a response element in the promoters of the CYP3A4 and ABCB1/MDR1 genes.
Protein Name Nuclear Receptor Subfamily 1 Group I Member 2
Orphan Nuclear Receptor Pxr
Pregnane X Receptor
Database Links Reactome: R-RNO-383280
Reactome: -RNO-4090294
Cellular Localisation Nucleus
Alternative ELISA Names Nuclear Receptor Subfamily 1 Group I Member 2 ELISA kit
Orphan Nuclear Receptor Pxr ELISA kit
Pregnane X Receptor ELISA kit
Nr1i2 ELISA kit
Pxr ELISA kit
output

Information sourced from Uniprot.org

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