Rat PTH1R protein (Recombinant) (N-His) (STJP010291)

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STJP010291
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Host: E.coli
Applications: ELISA/Immunogen/SDS-PAGE/WB
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Rat PTH1R-N-His protein was developed from e.coli for the region N-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Dilution Range: Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: Pth1r
Gene ID: 56813
Uniprot ID: PTH1R_RAT
Immunogen Region: Gly105-Asn176
Immunogen: Rattus norvegicus (Rat)
Function G-protein-coupled receptor for parathyroid hormone (PTH) and for parathyroid hormone-related peptide (PTHLH). Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of downstream effectors, such as adenylate cyclase (cAMP). PTH1R is coupled to G(s) G alpha proteins and mediates activation of adenylate cyclase activity. PTHLH dissociates from PTH1R more rapidly than PTH.as consequence, the cAMP response induced by PTHLH decays faster than the response induced by PTH.
Protein Name Parathyroid Hormone/Parathyroid Hormone-Related Peptide Receptor
Pth/Pthrp Type I Receptor
Pth/Pthr Receptor
Parathyroid Hormone 1 Receptor
Pth1 Receptor
Database Links Reactome: R-RNO-373080
Cellular Localisation Cell Membrane
Multi-Pass Membrane Protein
Alternative Protein Names Parathyroid Hormone/Parathyroid Hormone-Related Peptide Receptor protein
Pth/Pthrp Type I Receptor protein
Pth/Pthr Receptor protein
Parathyroid Hormone 1 Receptor protein
Pth1 Receptor protein
Pth1r protein
Pthr protein
Pthr1 protein

Information sourced from Uniprot.org

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