Name: Rat PS2 (Presenilin 2) Sandwich ELISA Kit Ready-To-Use Kit (STJE0018086)
SKU: STJE0018086
Availability: InStock

Rat PS2 (Presenilin 2) Sandwich ELISA Kit Ready-To-Use Kit (STJE0018086)

SKU:

STJE0018086

£497.50 - £682.50

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Applications:	ELISA
Reactivity:	Rat
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Sensitivity:	0.059ng/mL
Detection Limit:	0.156-10ng/mL
Short Description :	This PS2 Sandwich ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in rat tissue homogenates or other biological fluids..

Storage Instruction:	The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time:	3 hrs

Gene Symbol:	Psen2
Gene ID:	81751
Uniprot ID:	PSN2_RAT
Immunogen Region:	Ready-To-Use
Sample Type:	tissue homogenates or other biological fluids.

Tissue Specificity
Post Translational Modifications	Phosphorylated on serine residues.
Function	Probable catalytic subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors and APP (amyloid-beta precursor protein). Requires the other members of the gamma-secretase complex to have a protease activity. May play a role in intracellular signaling and gene expression or in linking chromatin to the nuclear membrane. May function in the cytoplasmic partitioning of proteins. The holoprotein functions as a calcium-leak channel that allows the passive movement of calcium from endoplasmic reticulum to cytosol and is involved in calcium homeostasis. Is a regulator of mitochondrion-endoplasmic reticulum membrane tethering and modulates calcium ions shuttling between ER and mitochondria.
Protein Name	Presenilin-2 Ps-2 Cleaved Into - Presenilin-2 Ntf Subunit - Presenilin-2 Ctf Subunit
Database Links	Reactome: R-RNO-1251985 Reactome: -RNO-193692 Reactome: -RNO-205043 Reactome: -RNO-3928665 Reactome: -RNO-9013507 Reactome: -RNO-9017802 Reactome: -RNO-9839383
Cellular Localisation	Endoplasmic Reticulum Membrane Multi-Pass Membrane Protein Golgi Apparatus Membrane
Alternative ELISA Names	Presenilin-2 ELISA kit Ps-2 Cleaved Into - Presenilin-2 Ntf Subunit - Presenilin-2 Ctf Subunit ELISA kit Psen2 ELISA kit Ps2 ELISA kit Psnl2 ELISA kit
output

Information sourced from Uniprot.org

Model	Name	Reactivity	Application
STJE0011700	Rat PS2 (Presenilin 2) Sandwich ELISA Kit Kit (STJE0011700)	Rat	ELISA
STJE0018944	Rat THBS2 (Thrombospondin 2) Sandwich ELISA Kit Ready-To-Use Kit (STJE0018944)	Rat	ELISA
STJE0017359	Rat NID2 (Nidogen 2) Sandwich ELISA Kit Ready-To-Use Kit (STJE0017359)	Rat	ELISA

Rat PS2 (Presenilin 2) Sandwich ELISA Kit Ready-To-Use Kit (STJE0018086)