Rat PPM1A (Protein Phosphatase, Mg2+/Mn2+ Dependent 1A) Sandwich ELISA Kit Kit (STJE0011621)

Rat PPM1A (Protein Phosphatase, Mg2+/Mn2+ Dependent 1A) Sandwich ELISA Kit Kit (STJE0011621)

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STJE0011621
£496.50 - £681.50
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Applications: ELISA
Reactivity: Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Sensitivity: 0.138ng/mL
Detection Limit: 0.312-20ng/mL
Short Description : This PPM1A Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in rat tissue homogenates, cell lysates or other biological fluids..
Storage Instruction: Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time: 4.5 hrs
Gene Symbol: Ppm1a
Gene ID: 24666
Uniprot ID: PPM1A_RAT
Sample Type: tissue homogenates, cell lysates or other biological fluids.
Tissue Specificity
Post Translational Modifications N-myristoylation is essential for the recognition of its substrates for dephosphorylation.
Function Enzyme with a broad specificity. Negatively regulates TGF-beta signaling through dephosphorylating SMAD2 and SMAD3, resulting in their dissociation from SMAD4, nuclear export of the SMADs and termination of the TGF-beta-mediated signaling. Dephosphorylates PRKAA1 and PRKAA2. Plays an important role in the termination of TNF-alpha-mediated NF-kappa-B activation through dephosphorylating and inactivating IKBKB/IKKB.
Protein Name Protein Phosphatase 1a
Protein Phosphatase 2c Isoform Alpha
Pp2c-Alpha
Protein Phosphatase Ia
Database Links Reactome: R-RNO-2173795
Reactome: -RNO-380972
Cellular Localisation Nucleus
Cytoplasm
Cytosol
Membrane
Lipid-Anchor
Weakly Associates At The Membrane And N-Myristoylation Mediates The Membrane Localization
Alternative ELISA Names Protein Phosphatase 1a ELISA kit
Protein Phosphatase 2c Isoform Alpha ELISA kit
Pp2c-Alpha ELISA kit
Protein Phosphatase Ia ELISA kit
Ppm1a ELISA kit
Pp2c1 ELISA kit
Pppm1a ELISA kit
output

Information sourced from Uniprot.org

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