Rat PDE1C (Phosphodiesterase 1C, Calmodulin Dependent) Sandwich ELISA Kit (STJE0011340)
SPECIFICATIONS
General Information
| Short Description | This PDE1C Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in rat tissue homogenates or other biological fluids.. |
| Applications | ELISA |
| Reactivity | Rat |
| Sensitivity | 0.042ng/mL |
| Detection Limit | 0.156-10ng/mL |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Storage Instruction | Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
| Assay Time | 4.5 hrs |
Target Information
| Gene Symbol | Pde1c |
| Gene ID | 81742 |
| Uniprot ID | PDE1C_RAT |
| Sample Type | tissue homogenates or other biological fluids. |
Additional Info
| Tissue Specificity | Highly expressed in olfactory epithelium and at moderate levels, in cerebellum, as well as weakly in forebrain, testis, heart and lung. In the olfactory epithelium, expressed by sensory neurons, but not epithelial cells. |
| Post Translational Modifications | |
| Function | Calmodulin-dependent cyclic nucleotide phosphodiesterase with a dual specificity for the second messengers cAMP and cGMP, which are key regulators of many important physiological processes. Has a high affinity for both cAMP and cGMP. Modulates the amplitude and duration of the cAMP signal in sensory cilia in response to odorant stimulation, hence contributing to the generation of action potentials. Regulates smooth muscle cell proliferation. Regulates the stability of growth factor receptors, including PDGFRB. |
| Protein Name | Dual Specificity Calcium/Calmodulin-Dependent 3' -5'-Cyclic Nucleotide Phosphodiesterase 1cCam-Pde 1c |
| Database Links | Reactome: R-RNO-111957 |
| Cellular Localisation | Lysosome |
| Alternative ELISA Names | Dual Specificity Calcium/Calmodulin-Dependent 3' -5'-Cyclic Nucleotide Phosphodiesterase 1c ELISA kitCam-Pde 1c ELISA kitPde1c ELISA kitPde1c2 ELISA kit |
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Information sourced from Uniprot.org