| Tissue Specificity | |
| Post Translational Modifications | |
| Function | Calcium-binding protein which may have a role in calcium homeostasis. Acts as a non-receptor guanine nucleotide exchange factor which binds to and activates guanine nucleotide-binding protein (G-protein) alpha subunit GNAI3. Nesfatin-1: Anorexigenic peptide, seems to play an important role in hypothalamic pathways regulating food intake and energy homeostasis, acting in a leptin-independent manner. May also exert hypertensive roles and modulate blood pressure through directly acting on peripheral arterial resistance. In intestinal epithelial cells, plays a role in the inhibition of hepatic glucose production via MC4R receptor leading to increased cyclic adenosine monophosphate (cAMP) levels and glucagon-like peptide 1 (GLP-1) secretion. |
| Protein Name | Nucleobindin-2Dna-Binding Protein NefaPrepronesfatin Cleaved Into - Nesfatin-1 |
| Database Links | |
| Cellular Localisation | Golgi ApparatusEndoplasmic ReticulumNucleus EnvelopeMembranePeripheral Membrane ProteinCytoplasmSecretedNesfatin-1: Secreted |
| Alternative ELISA Names | Nucleobindin-2 ELISA kitDna-Binding Protein Nefa ELISA kitPrepronesfatin Cleaved Into - Nesfatin-1 ELISA kitNucb2 ELISA kitNefa ELISA kit |
| output | |
Information sourced from Uniprot.org
