| Tissue Specificity | Detected in liver (at protein level). Expressed in liver. |
| Post Translational Modifications | S-nitrosylation of Cys-121 inactivates the enzyme. An intrachain disulfide bond can be formed. The protein structure shows that the relevant Cys residues are in a position that would permit formation of a disulfide bond. |
| Function | Catalyzes the formation of S-adenosylmethionine from methionine and ATP. The reaction comprises two steps that are both catalyzed by the same enzyme: formation of S-adenosylmethionine (AdoMet) and triphosphate, and subsequent hydrolysis of the triphosphate. |
| Protein Name | S-Adenosylmethionine Synthase Isoform Type-1Adomet Synthase 1Methionine Adenosyltransferase 1Mat 1Methionine Adenosyltransferase I/IiiMat-I/Iii |
| Database Links | Reactome: R-RNO-156581Reactome: -RNO-1614635Reactome: -RNO-2408508 |
| Cellular Localisation | |
| Alternative ELISA Names | S-Adenosylmethionine Synthase Isoform Type-1 ELISA kitAdomet Synthase 1 ELISA kitMethionine Adenosyltransferase 1 ELISA kitMat 1 ELISA kitMethionine Adenosyltransferase I/Iii ELISA kitMat-I/Iii ELISA kitMat1a ELISA kitAms1 ELISA kit |
| output | |
Information sourced from Uniprot.org
