Rat IL-1 Beta (Interleukin-1 Beta) Antibody Pair (STJAP00093)
General Information
| Short Description | This IL-1 Beta antibody pair contains complimentary capture and detection antibodies, which work together under the principals of the Sandwich ELISA. |
| Applications | ELISA |
| Host | Goat/Goat |
| Reactivity | Rat |
| Note | FOR SCIENTIFIC EDUCATIONAL RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR OTHER MEDICAL APPLICATIONS. |
Product Properties
| Clonality | Polyclonal/Polyclonal |
| Conjugation | Unconjugated/Biotin |
| Concentration | 0.5 mg/mL |
| Purification | Capture Purification: Antigen Affinity.Detection Purification: Antigen Affinity. |
| Formulation | Capture Buffer: PBS with 0.04% Proclin 300, 50% glycerol, pH 7.4.Detection Buffer: PBS with 0.04% Proclin 300, 50% glycerol, pH 7.4. |
| Storage Instruction | Store at-20°C for the long term, and avoid freeze-thaw cycles. |
Target Information
| Gene Symbol | Il1bUniprot ID=IL1B_RAT" |
| Immunogen | Capture immunogen: Recombinant Rat IL-1 Beta protein.Detection Immunogen: Recombinant Rat IL-1 Beta protein. |
Additional Info
| Protein Name | Interleukin-1 BetaIl-1 Beta |
| Cellular Localisation | CytoplasmCytosolSecretedLysosomeExtracellular ExosomeThe Precursor Is CytosolicIn Response To Inflammasome-Activating SignalsSuch As Atp For Nlrp3 Inflammasome Or Bacterial Flagellin For Nlrc4 InflammasomeCleaved And SecretedMature Form Is Secreted And Released In The Extracellular Milieu By Passing Through The Gasdermin-D (Gsdmd) PoreIn ContrastThe Precursor Form Is Not ReleasedDue To The Presence Of An Acidic Region That Is Proteolytically Removed By Casp1 During MaturationThe Secretion Is Dependent On Protein Unfolding And Facilitated By The Cargo Receptor Tmed10 |
| Alternative Antibody Pair Names | Interleukin-1 Beta antibody pairIl-1 Beta antibody pairIl1b antibody pair |
Information sourced from Uniprot.org
Citations
Product Review
Frequently Asked Questions
Common questions about Rat IL-1 Beta (Interleukin-1 Beta) Antibody Pair (STJAP00093)
This antibody pair detects rat IL-1 Beta (Interleukin-1 Beta), corresponding to UniProt entry Q63264. Reactivity is confirmed for rat only.
Both antibodies are polyclonal, raised in goat, and purified by antigen affinity. The capture antibody is unconjugated, while the detection antibody is biotinylated. Both are supplied at 0.5 mg/mL in PBS with 0.04% Proclin 300 and 50% glycerol at pH 7.4.
This pair has been validated for use in ELISA. No other assay formats are listed in the product documentation.
Both antibodies were raised against recombinant rat IL-1 Beta protein. Specific immunogen regions are not detailed in the product specifications.
Both components should be stored at -20°C for long-term storage. Freeze-thaw cycles should be avoided to maintain antibody integrity.
Specific cross-reactivity or species cross-reactivity data are not provided in the current product specifications. Reactivity is confirmed for rat only, and this product is intended for research use only.
Orders typically arrive within 1 to 2 weeks, and often sooner depending on your location. If your timeline is critical, please contact us before ordering and we can advise on current lead times.
This product is shipped on gel ice packs to maintain integrity during transit. Priority shipping is used as standard to minimise time in transit.
A Certificate of Analysis (CoA) is provided with every order. If you do not receive one, please contact us and we will issue it promptly.