Tissue Specificity | |
Post Translational Modifications | |
Function | Glutathione S-transferase that catalyzes the nucleophilic attack of the sulfur atom of glutathione on the electrophilic groups of a wide range of exogenous and endogenous compounds (Probable). Involved in the formation of glutathione conjugates of both prostaglandin A2 (PGA2) and prostaglandin J2 (PGJ2). It also catalyzes the isomerization of D5-androstene-3,17-dione (AD) into D4-androstene-3,17-dione and may therefore play an important role in hormone biosynthesis. Through its glutathione-dependent peroxidase activity toward the fatty acid hydroperoxide (13S)-hydroperoxy-(9Z,11E)-octadecadienoate/13-HPODE it is also involved in the metabolism of oxidized linoleic acid. |
Protein Name | Glutathione S-Transferase Alpha-113-Hydroperoxyoctadecadienoate PeroxidaseAndrost-5-Ene-3 -17-Dione IsomeraseGst 1-1Gst 1a-1aGst A1-1Gst BGlutathione S-Transferase Ya-1Gst Ya1Ligandin |
Database Links | Reactome: R-RNO-156590Reactome: -RNO-189483Reactome: -RNO-9748787 |
Cellular Localisation | Cytoplasm |
Alternative ELISA Names | Glutathione S-Transferase Alpha-1 ELISA kit13-Hydroperoxyoctadecadienoate Peroxidase ELISA kitAndrost-5-Ene-3 -17-Dione Isomerase ELISA kitGst 1-1 ELISA kitGst 1a-1a ELISA kitGst A1-1 ELISA kitGst B ELISA kitGlutathione S-Transferase Ya-1 ELISA kitGst Ya1 ELISA kitLigandin ELISA kitGsta1 ELISA kit |
output | |
Information sourced from Uniprot.org