Rat GPI (Glucose 6 Phosphate Isomerase) Sandwich ELISA Kit (STJE0007099)
SPECIFICATIONS
General Information
| Short Description | This GPI Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in rat serum, plasma or other biological fluids.. |
| Applications | ELISA |
| Reactivity | Rat |
| Sensitivity | 5.9pg/mL |
| Detection Limit | 15.6-1000pg/mL |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Storage Instruction | Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
| Assay Time | 4.5 hrs |
Target Information
| Gene Symbol | Gpi |
| Gene ID | 292804 |
| Uniprot ID | G6PI_RAT |
| Sample Type | serum, plasma or other biological fluids. |
Additional Info
| Tissue Specificity | |
| Post Translational Modifications | Phosphorylation at Ser-185 by CK2 has been shown to decrease enzymatic activity and may contribute to secretion by a non-classical secretory pathway. ISGylated. |
| Function | In the cytoplasm, catalyzes the conversion of glucose-6-phosphate to fructose-6-phosphate, the second step in glycolysis, and the reverse reaction during gluconeogenesis. Besides it's role as a glycolytic enzyme, also acts as a secreted cytokine: acts as an angiogenic factor (AMF) that stimulates endothelial cell motility. Acts as a neurotrophic factor, neuroleukin, for spinal and sensory neurons. It is secreted by lectin-stimulated T-cells and induces immunoglobulin secretion. |
| Protein Name | Glucose-6-Phosphate IsomeraseGpiAutocrine Motility FactorAmfNeuroleukinNlkPhosphoglucose IsomerasePgiPhosphohexose IsomerasePhi |
| Database Links | Reactome: R-RNO-5628897Reactome: -RNO-6798695Reactome: -RNO-70171Reactome: -RNO-70263 |
| Cellular Localisation | CytoplasmSecreted |
| Alternative ELISA Names | Glucose-6-Phosphate Isomerase ELISA kitGpi ELISA kitAutocrine Motility Factor ELISA kitAmf ELISA kitNeuroleukin ELISA kitNlk ELISA kitPhosphoglucose Isomerase ELISA kitPgi ELISA kitPhosphohexose Isomerase ELISA kitPhi ELISA kitGpi ELISA kit |
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Information sourced from Uniprot.org